Liverpool Epidemic Strain Isolates of Pseudomonas aeruginosa Display High Levels of Antimicrobial Resistance during Both Planktonic and Biofilm Growth-Reference-Cited by-同舟云学术

Liverpool Epidemic Strain Isolates of Pseudomonas aeruginosa Display High Levels of Antimicrobial Resistance during Both Planktonic and Biofilm Growth

Published:2022-06-29 Issue:3 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Goodyear Mara C.¹,Garnier Nicole E.¹,Levesque Roger C.²,Khursigara Cezar M.¹^ORCID

Affiliation:

1. Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada

2. Institut de Biologie Integrative et des Systems (IBIS), Département de Microbiologie-Infectiologie et d'Immunologie, Université Laval, Laval, Quebec, Canada

Abstract

Pseudomonas aeruginosa is an opportunistic pathogen with high intrinsic antibiotic resistance. This resistance is typically increased in clinical isolates through adaptations to the host and production of small-colony variants (SCVs) and when P. aeruginosa forms biofilms, which are surface-attached communities that are protected by a self-produced matrix.

Funder

Gouvernement du Canada | Canadian Institutes of Health Research

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.01024-22

Reference46 articles.

1. Mechanisms of antibiotic resistance in Pseudomonas aeruginosa;Lambert PA;J R Soc Med,2002

2. The Building Blocks of Antimicrobial Resistance in Pseudomonas aeruginosa: Implications for Current Resistance-Breaking Therapies

3. Cystic Fibrosis Foundation. 2022. Antibiotics. https://www.cff.org/managing-cf/antibiotics.

4. Antibiotic Management of Lung Infections in Cystic Fibrosis. I. The Microbiome, Methicillin-ResistantStaphylococcus aureus, Gram-Negative Bacteria, and Multiple Infections

5. Tolerance and Resistance of Pseudomonas aeruginosa Biofilms to Antimicrobial Agents—How P. aeruginosa Can Escape Antibiotics

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Evaluation of treatment of methicillin-resistant Staphylococcus aureus biofilms with intermittent electrochemically generated H ₂ O ₂ or HOCl;Antimicrobial Agents and Chemotherapy;2024-07-09

2. The Impact of Antimicrobial Resistance in Cystic Fibrosis;Journal of Clinical Medicine;2024-03-16

3. Quantitative proteomics reveals unique responses to antimicrobial treatments in clinical Pseudomonas aeruginosa isolates;mSystems;2023-10-26

4. Discovery of Novel Resistance Mechanisms of Vibrio parahaemolyticus Biofilm against Aminoglycoside Antibiotics;Antibiotics;2023-03-24

5. Machine Learning Techniques for Antimicrobial Resistance Prediction of Pseudomonas Aeruginosa from Whole Genome Sequence Data;Computational Intelligence and Neuroscience;2023-03-01