Bacterial Swarm-Mediated Phage Transportation Disrupts a Biofilm Inherently Protected from Phage Penetration

Author:

Ratheesh Nichith K.1,Zdimal Amanda M.1,Calderon Cole A.1,Shrivastava Abhishek1ORCID

Affiliation:

1. Biodesign Center for Fundamental and Applied Microbiomics, School of Life Sciences, Center for Biological Physics, Arizona State University, Tempe, Arizona, USA

Abstract

Dysbiosis of the human oral microbiota is associated with several diseases, but the factors that shape the biogeography of the oral microbiota are mostly opaque. Biofilms that form in the human supragingival and subgingival regions have a diverse microbial community where some microbes form well-defined polymicrobial structures. C. gingivalis , a bacterium abundant in human gingival regions, has robust gliding motility that is powered by the type 9 secretion system.

Funder

NIH-NIDCR

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Reference35 articles.

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