Synergistic Effects of Licorice Root and Walnut Leaf Extracts on Gastrointestinal Candidiasis, Inflammation and Gut Microbiota Composition in Mice-Reference-Cited by-同舟云学术

Synergistic Effects of Licorice Root and Walnut Leaf Extracts on Gastrointestinal Candidiasis, Inflammation and Gut Microbiota Composition in Mice

Published:2022-04-27 Issue:2 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Authier Hélène¹^ORCID,Bardot Valérie²,Berthomier Lucile²,Bertrand Bénédicte¹,Blondeau Claude³,Holowacz Sophie³,Coste Agnès¹^ORCID

Affiliation:

1. Geroscience and Rejuvenation Research Center (RESTORE), UMR 1301-Inserm 5070-CNRS EFS, Université P. Sabatier, Toulouse, France

2. PiLeJe Industrie, Saint-Bonnet-de-Rochefort, France

3. PiLeJe Laboratoire, Paris, France

Abstract

The adverse effects and emergence of resistance of currently available antifungals and the high recurrence of candidiasis prompt the need for alternative and complementary strategies. We demonstrated that oral administration of hydroethanolic extracts of licorice root (LRE) and walnut leaf (WLE) separately or in combination significantly reduced the colonization of the gastrointestinal (GI) tract by C. albicans , highlighting a robust antifungal activity of these plant extracts.

Funder

Pileje Laboratoire, Paris, France

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.02355-21

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