Specific Plasma MicroRNA Signatures Underlying the Clinical Outcomes of Hepatitis E Virus Infection-Reference-Cited by-同舟云学术

Specific Plasma MicroRNA Signatures Underlying the Clinical Outcomes of Hepatitis E Virus Infection

Published:2023-02-14 Issue:1 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Costafreda Maria I.¹²³⁴^ORCID,Sauleda Silvia¹²³,Riveiro-Barciela Mar²⁵,Rico Angie¹,Llorens-Revull Meritxell²³,Guix Susana⁴^ORCID,Pintó Rosa M.⁴^ORCID,Bosch Albert⁴^ORCID,Rodríguez-Frías Francisco²⁶,Rando Ariadna²⁶^ORCID,Piron Maria¹²³,Bes Marta¹²³

Affiliation:

1. Blood and Tissue Bank of Catalonia (Banc de Sang i Teixits de Catalunya), Transfusion Safety Laboratory, Barcelona, Spain

2. Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREhd), Instituto de Salud Carlos III, Madrid, Spain

3. Vall d’Hebron Institute of Research (VHIR), Vall d’Hebron Universitary Hospital, Barcelona, Spain

4. Enteric Virus Laboratory, Department of Genetics, Microbiology and Statistics, School of Biology, and Institute of Nutrition and Safety, University of Barcelona, Barcelona, Spain

5. Liver Unit, Internal Medicine Department, Vall d’Hebron Universitary Hospital and Universitat Autonoma de Barcelona, Barcelona, Spain

6. Liver Pathology Laboratory, Microbiology and Biochemistry Department, Vall d’Hebron Clinical Laboratories, Vall d’Hebron Universitary Hospital, Barcelona, Spain

Abstract

There is increasing evidence that viruses dysregulate the expression and/or secretion of microRNAs to promote viral replication, immune evasion, and pathogenesis. In this study, we evaluated the change in microRNA abundance in patients with acute or chronic HEV infection and asymptomatic HEV-infected blood donors.

Funder

Banc de Sang i Teixits

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.04664-22

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