Efficacy in Galleria mellonella Larvae and Application Potential Assessment of a New Bacteriophage BUCT700 Extensively Lyse Stenotrophomonas maltophilia

Author:

Li Yahao1,Pu Mingfang2,Han Pengjun2,Li Mengzhe2,An Xiaoping2,Song Lihua2,Fan Huahao2ORCID,Chen Zeliang34,Tong Yigang12

Affiliation:

1. Beijing Advanced Innovation Center for Soft Matter Science and Engineering (BAIC-SM), Beijing University of Chemical Technology, Beijing, China

2. College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China

3. Key Laboratory of Tropical Diseases Control, Sun Yat-Sen University, Ministry of Education, Guangzhou, China

4. Key Laboratory of Zoonose Prevention and Control at Universities of Inner Mongolia Autonomous Region, Tongliao, China

Abstract

The risk of Stenotrophomonas maltophilia infections mediated by the medical devices is exacerbated with an increase in the number of ICU patients during the Corona Virus Disease 2019 (COVID-19) epidemic. Complications caused by S. maltophilia infections could complicate the state of an illness, greatly extending the length of hospitalization and increasing the financial burden.

Funder

National Key Research and Development Program of China

Funds for First-class Discipline Construction

Inner Mongolia Key Research and Development Program

NSFC-MFST project

Fundamental Research Funds for Central Universities

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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