LexR Positively Regulates the LexABC Efflux Pump Involved in Self-Resistance to the Antimicrobial Di- <i>N</i> -Oxide Phenazine in Lysobacter antibioticus-Reference-Cited by-同舟云学术

LexR Positively Regulates the LexABC Efflux Pump Involved in Self-Resistance to the Antimicrobial Di- N -Oxide Phenazine in Lysobacter antibioticus

Published:2023-06-15 Issue:3 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Zhao Yangyang¹²^ORCID,Xu Gaoge¹^ORCID,Xu Zhizhou¹³,Guo Baodian¹,Liu Fengquan¹²

Affiliation:

1. Institute of Plant Protection, Jiangsu Academy of Agricultural Sciences, Jiangsu Key Laboratory for Food Quality and Safety, State Key Laboratory Cultivation Base of Ministry of Science and Technology, Nanjing, China

2. School of Plant Protection, Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests, Ministry of Education, Hainan University, Haikou, China

3. College of Plant Protection, Key Laboratory of Integrated Management of Crop Diseases and Pests, Nanjing Agricultural University, Nanjing, China

Abstract

Antibiotic-producing bacteria exhibit various sophisticated mechanisms for self-protection against their own secondary metabolites. RND efflux pumps that eliminate antibiotics from cells are ubiquitous in Gram-negative bacteria.

Funder

China Agriculture Research System

MOST | National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.04872-22

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