A Saliva-Based Serological and Behavioral Analysis of SARS-CoV-2 Antibody Prevalence in Howard County, Maryland-Reference-Cited by-同舟云学术

A Saliva-Based Serological and Behavioral Analysis of SARS-CoV-2 Antibody Prevalence in Howard County, Maryland

Published:2023-08-17 Issue:4 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Brown Alan C.¹,Koshute Phillip T.¹,Cowley Hannah P.¹,Robinette Michael S.¹,Gravelyn Sarah R.¹,Patel Shraddha V.¹,Ju Eunice Y.¹,Frommer Carolyn T.¹,Zambidis Alexander E.¹,Schneider Eric J.¹,Zhao Martina Y.¹,Mugo Benny K.¹,Clarke William²,Kruczynski Kate³,Pisanic Nora³,Heaney Christopher D.³^ORCID,Colella Teresa A.¹^ORCID

Affiliation:

1. Johns Hopkins University Applied Physics Laboratory, Laurel, Maryland, USA

2. Johns Hopkins Medicine, Baltimore, Maryland, USA

3. Johns Hopkins Environmental Health Microbiology and Immunology Laboratory (JH-EHMIL), Bloomberg School of Public Health, Baltimore, Maryland, USA

Abstract

We employed a highly innovative noninvasive multiplex oral fluid SARS-CoV-2 IgG assay to ascertain our seroprevalence estimates. This laboratory-developed test has been applied in NCI’s SeroNet consortium, possesses high sensitivity and specificity according to FDA Emergency Use Authorization guidelines, correlates strongly with SARS-CoV-2 neutralizing antibody responses, and is Clinical Laboratory Improvement Amendments-approved by the Johns Hopkins Hospital Department of Pathology.

Funder

Howard County, Maryland Government

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.02765-22

Reference24 articles.

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2. Assessing the Impact of the Covid-19 Pandemic on US Mortality: A County-Level Analysis

3. Estimated Community Seroprevalence of SARS-CoV-2 Antibodies — Two Georgia Counties, April 28–May 3, 2020

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5. Estimated US Infection- and Vaccine-Induced SARS-CoV-2 Seroprevalence Based on Blood Donations, July 2020-May 2021

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