N 6 -Methyladenosine RNA Modification in Host Cells Regulates Peste des Petits Ruminants Virus Replication

Author:

Khan Owais1,Tanuj Gunturu Narasimha1,Choravada Divyaprakash R.1,Rajak Kaushal Kishore2,Chandra Sekar S3,Lingaraju Madhu Cholenahalli4,Dhara Sujoy K.1,Gupta Praveen K.1,Mishra Bishnu Prasad5,Dutt Triveni1,Gandham Ravi Kumar1,Sajjanar Basavaraj1ORCID

Affiliation:

1. Veterinary Biotechnology Division, ICAR—Indian Veterinary Research Institute, Izatnagar Bareilly, Uttar Pradesh, India

2. Biological Products Division, ICAR—Indian Veterinary Research Institute, Izatnagar Bareilly, Uttar Pradesh, India

3. Division of Virology, ICAR—Indian Veterinary Research Institute, Mukteshwar, Uttarakhand, India

4. Pharmacology and Toxicology Division, ICAR—Indian Veterinary Research Institute, Izatnagar Bareilly, Uttar Pradesh, India

5. ICAR—National Bureau of Animal Genetic Resources, Karnal, Haryana, India

Abstract

Peste des petits ruminants virus (PPRV) causes a severe disease in sheep and goats. PPRV infection is a major problem, causing significant economic losses to small ruminant farmers in regions of endemicity.

Funder

The Wellcome Trust DBT India Alliance

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Reference49 articles.

1. Virus Infection

2. Determining Host Metabolic Limitations on Viral Replication via Integrated Modeling and Experimental Perturbation

3. Viral hijacking of cellular metabolism

4. Rampersad S, Tennant P. 2018. Replication and expression strategies of viruses, p 55–82. In Tennant P, Fermin G, Foster JE (ed), Viruses: molecular biology, host interactions and applications to biotechnology. Academic Press, Cambridge, MA.

5. Viral infection linked to m6A alterations in host mRNAs

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