Comparison of a Rapid Multiplex Gastrointestinal Panel with Standard Laboratory Testing in the Management of Children with Hematochezia in a Pediatric Emergency Department: Randomized Controlled Trial-Reference-Cited by-同舟云学术

Comparison of a Rapid Multiplex Gastrointestinal Panel with Standard Laboratory Testing in the Management of Children with Hematochezia in a Pediatric Emergency Department: Randomized Controlled Trial

Published:2023-06-15 Issue:3 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Xie Jianling¹,Kim Kelly¹,Berenger Byron M.²³,Chui Linda⁴⁵^ORCID,Vanderkooi Otto G.⁶,Grisaru Silviu⁷,Freedman Stephen B.¹⁸^ORCID

Affiliation:

1. Section of Pediatric Emergency Medicine, Department of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

2. Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

3. Alberta Precision Laboratories, Alberta Health Services, Calgary, Alberta, Canada

4. Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada

5. Alberta Precision Laboratories, Alberta Health Services, Edmonton, Alberta, Canada

6. Section of Infectious Diseases, Department of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

7. Section of Pediatric Nephrology, Department of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

8. Section of Pediatric Gastroenterology, Department of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada

Abstract

Advances in diagnostic microbiology now allow for the faster and more accurate detection of an increasing number of pathogens. We determined, however, that in children with acute bloody diarrhea, these advances did not necessarily translate into improved clinical outcomes.

Funder

Alberta Children’s Hospital

Alberta Children's Hospital Foundation

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00268-23

Reference43 articles.

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3. Böhrer M Fitzpatrick E Hurley K et al. 2021. Hematochezia in children with acute diarrhea seeking emergency department care: a prospective cohort study. Acad Emerg Med.

4. Predicting Hemolytic Uremic Syndrome and Renal Replacement Therapy in Shiga Toxin–producing Escherichia coli–infected Children

5. Shiga Toxin-Associated Hemolytic Uremic Syndrome: A Narrative Review

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