RG203KR Mutations in SARS-CoV-2 Nucleocapsid: Assessing the Impact Using a Virus-Like Particle Model System-Reference-Cited by-同舟云学术

RG203KR Mutations in SARS-CoV-2 Nucleocapsid: Assessing the Impact Using a Virus-Like Particle Model System

Published:2022-08-31 Issue:4 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Raheja Harsha¹,Das Soma²,Banerjee Anindita³,P. Dikshaya¹,C. Deepika¹,Mukhopadhyay Debanjan³,Ramachandra Subbaraya G.⁴,Das Saumitra¹³^ORCID

Affiliation:

1. Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India

2. Department of Biochemistry, Indian Institute of Science, Bangalore, India

3. National Institute of Biomedical Genomics, Kalyani, India

4. Central Animal Facility, Indian Institute of Science, Bangalore, India

Abstract

Since its origin in late 2019, the SARS-CoV-2 virus has been constantly mutating and evolving. Current studies mostly employ spike protein (S) pseudovirus systems to determine the effects of mutations on the infectivity and immunogenicity of variants.

Funder

Department of Biotechnology, Ministry of Science and Technology, India

Department of Science and Technology, Ministry of Science and Technology, India

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00781-22

Reference18 articles.

1. Epidemiology, Genetic Recombination, and Pathogenesis of Coronaviruses

2. COVID-19: angiotensin-converting enzyme 2 (ACE2) expression and tissue susceptibility to SARS-CoV-2 infection