Development of a Heat-Killed <i>fbp1</i> Mutant Strain as a Therapeutic Agent To Treat Invasive Cryptococcus Infection-Reference-Cited by-同舟云学术

Development of a Heat-Killed fbp1 Mutant Strain as a Therapeutic Agent To Treat Invasive Cryptococcus Infection

Published:2023-04-13 Issue:2 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Wang Yina¹,Wang Keyi²,Rivera Amariliz³⁴^ORCID,Xue Chaoyang¹⁵^ORCID

Affiliation:

1. Public Health Research Institute, New Jersey Medical School, Rutgers University, Newark, New Jersey, USA

2. Graduate School of Biomedical Sciences, New Jersey Medical School, Rutgers University, Newark, New Jersey, USA

3. Department of Pediatrics, New Jersey Medical School, Rutgers University, Newark, New Jersey, USA

4. Center for Immunity and Inflammation, New Jersey Medical School, Rutgers University, Newark, New Jersey, USA

5. Department of Microbiology, Biochemistry and Molecular Genetics, New Jersey Medical School, Rutgers University, Newark, New Jersey, USA

Abstract

Invasive fungal infections, e.g., cryptococcosis, are often life threatening and difficult to treat with very limited therapeutic options. There is no vaccine available in clinical use to prevent or treat fungal infections.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | NIH | National Heart, Lung, and Blood Institute

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.04955-22

Reference36 articles.

1. Global and Multi-National Prevalence of Fungal Diseases—Estimate Precision

2. Drug-Resistant Fungi: An Emerging Challenge Threatening Our Limited Antifungal Armamentarium

3. Current perspectives on echinocandin class drugs

4. Harnessing the Immune Response to Fungal Pathogens for Vaccine Development

5. A Fungal Immunotherapeutic Vaccine (NDV-3A) for Treatment of Recurrent Vulvovaginal Candidiasis—A Phase 2 Randomized, Double-Blind, Placebo-Controlled Trial

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Recent advances in the clinical development of antifungal vaccines: a narrative review;Frontiers in Tropical Diseases;2024-08-08

2. Inbred Mouse Models in Cryptococcus neoformans Research;Journal of Fungi;2024-06-17

3. Lack of an atypical PDR transporter generates an immunogenicCryptococcus neoformansstrain that drives a dysregulated and lethal immune response in murine lungs;2024-06-17

4. Vaccine Strategies for Cryptococcus neoformans;Methods in Molecular Biology;2024

5. Dendritic Cells: Multifunctional Roles in Host Defenses to Cryptococcus Infections;Journal of Fungi;2023-10-26