Isolation of an Extensively Drug-Resistant Pseudomonas aeruginosa exoS + /O4 Strain Belonging to the “High-Risk” Clone ST654 and Coproducer of NDM-1 and the Novel VIM-80

Author:

Opazo-Capurro Andrés12ORCID,Morales-León Felipe123,Jerez Christian14,Olivares-Pacheco Jorge25,Alcalde-Rico Manuel25,González-Muñoz Paulina16,Bello-Toledo Helia12ORCID,Cardenas-Arias Adriana7,Esposito Fernanda8,Lincopán Nilton78ORCID,Illesca Vijna9,González-Rocha Gerardo12ORCID

Affiliation:

1. Laboratorio de Antibióticos, Departamento de Microbiología, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción, Chile

2. Millennium Nucleus for Collaborative Research on Bacterial Resistance, Santiago, Chile

3. Departamento de Farmacia, Facultad de Farmacia, Universidad de Concepción, Concepción, Chile

4. Department of Restorative School of Dentistry, University of Concepción, Concepción, Chile

5. Grupo de Resistencia Antibacteriana en Bacterias Patógenas Ambientales GRABPA, Instituto de Biología, Pontificia Universidad Católica de Valparaíso, Valparaíso, Chile

6. Departamento de Ciencias Biológicas y Químicas, Facultad de Medicina y Ciencia, Universidad San Sebastián, Concepción, Chile

7. Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil

8. Department of Clinical Analysis, School of Pharmacy, University of São Paulo, São Paulo, Brazil

9. Hospital Hernán Henríquez Aravena, Clinical Laboratory, Temuco, Chile

Abstract

The aim of this study was to investigate the genomic features of an extensively drug-resistant (XDR) Pseudomonas aeruginosa isolate (P-469) emerging in Chile. Antibiotic susceptibility was determined by disk diffusion and “colistin agar” test.

Funder

ANID | Fondo Nacional de Desarrollo Científico y Tecnológico

Pfizer

Agencia Nacional de Investigación y Desarrollo

Fundação de Amparo à Pesquisa do Estado de São Paulo

PND/CAPES

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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