The Cystic Fibrosis Upper and Lower Airway Metagenome-Reference-Cited by-同舟云学术

The Cystic Fibrosis Upper and Lower Airway Metagenome

Published:2023-04-13 Issue:2 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Pienkowska Katarzyna¹,Pust Marie-Madlen¹²,Gessner Margaux¹,Gaedcke Svenja²,Thavarasa Ajith¹,Rosenboom Ilona¹,Morán Losada Patricia¹,Minso Rebecca¹,Arnold Christin³,Hedtfeld Silke¹,Dorda Marie¹⁴,Wiehlmann Lutz¹²⁴,Mainz Jochen G.³⁵,Klockgether Jens¹,Tümmler Burkhard¹²^ORCID

Affiliation:

1. Department for Pediatric Pneumology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany

2. Biomedical Research in Endstage and Obstructive Lung Disease, German Center for Lung Research, Hannover, Germany

3. Cystic Fibrosis Center for Children and Adults, Jena University Hospital, Jena, Germany

4. Research Core Unit Genomics, Hannover Medical School, Hannover, Germany

5. Klinik für Kinder- und Jugendmedizin, Medizinische Hochschule Brandenburg, Brandenburg, Germany

Abstract

Cystic fibrosis (CF) is the most common life-limiting monogenetic disease in European populations and is caused by mutations in the CFTR gene. Chronic airway infections with opportunistic pathogens are the major morbidity that determines prognosis and quality of life in most people with CF.

Funder

Bundesministerium für Bildung und Forschung

Deutsche Forschungsgemeinschaft

Else Kröner-Fresenius-Stiftung

Studienstiftung des Deutschen Volkes

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.03633-22

Reference91 articles.