Time Series Analysis of SARS-CoV-2 Genomes and Correlations among Highly Prevalent Mutations

Author:

Periwal Neha1,Rathod Shravan B.2,Sarma Sankritya3,Johar Gundeep S.4,Jain Avantika15,Barnwal Ravi P.6,Srivastava Kinsukh R.7,Kaur Baljeet8,Arora Pooja3,Sood Vikas1ORCID

Affiliation:

1. Department of Biochemistry, SCLS, Jamia Hamdard, New Delhi, India

2. Department of Chemistry, Smt. S. M. Panchal Science College, Talod, Gujarat, India

3. Department of Zoology, Hansraj College, University of Delhi, New Delhi, India

4. Humber College, Toronto, Ontario, Canada

5. Delhi Institute of Pharmaceutical Sciences and Research, New Delhi, Delhi, India

6. Department of Biophysics, Panjab University, Chandigarh, India

7. Division of Medicinal and Process Chemistry, CDRI, Lucknow, Uttar Pradesh, India

8. Department of Computer Science, Hansraj College, University of Delhi, New Delhi, India

Abstract

We performed a meta-analysis on SARS-CoV-2 genomes categorized by collection month and identified several significant mutations. Pearson correlation analysis of these significant mutations identified 16 comutations having absolute correlation coefficients of >0.4 and a frequency of >30% in the genomes used in this study.

Funder

University Grants Commission

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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