Persistent Anti- Borrelia IgM Antibodies without Lyme Borreliosis in the Clinical and Immunological Context-Reference-Cited by-同舟云学术

Persistent Anti- Borrelia IgM Antibodies without Lyme Borreliosis in the Clinical and Immunological Context

Published:2021-12-22 Issue:3 Volume:9 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Markowicz Mateusz¹^ORCID,Reiter Michael¹,Gamper Jutta²,Stanek Gerold¹,Stockinger Hannes¹

Affiliation:

1. Institute for Hygiene and Applied Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria

2. Center for Medical Statistics, Informatics and Intelligent Systems, Section for Medical Statistics, Medical University of Vienna, Vienna, Austria

Abstract

The reactivity of human IgM with the outer surface protein C (OspC) of Borrelia burgdorferi sensu lato is frequently used to detect Borrelia specific IgM in commercial immunoassays, and such antibodies usually occur in the early phase of the infection. We identified a group of individuals with persistent Borrelia IgM without symptoms of Lyme borreliosis.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/Spectrum.01020-21

Reference24 articles.

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2. Lyme borreliosis: Clinical case definitions for diagnosis and management in Europe

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2. In silico epitope prediction of Borrelia burgdorferi sensu lato antigens for the detection of specific antibodies;Journal of Immunological Methods;2024-01

3. Profiling disease burden and Borrelia seroprevalence in Canadians with complex and chronic illness;PLOS ONE;2023-11-08

4. Features of the immune response in early period of ixodid tick-borne borreliosis;Epidemiology and Infectious Diseases;2023-11-05

5. Antibody Cross-Reactivity in Serodiagnosis of Lyme Disease;Antibodies;2023-10-05