The Mechanism of Action of Ginkgolic Acid (15:1) against Gram-Positive Bacteria Involves Cross Talk with Iron Homeostasis-Reference-Cited by-同舟云学术

The Mechanism of Action of Ginkgolic Acid (15:1) against Gram-Positive Bacteria Involves Cross Talk with Iron Homeostasis

Published:2022-02-23 Issue:1 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Wen Zewen¹²^ORCID,Zhao Yuxi¹²,Gong Zhengyang¹²,Tang Yuanyuan¹²,Xiong Yanpeng¹²,Chen Junwen¹²,Chen Chengchun¹²,Zhang Yufang¹³,Liu Shanghong¹²,Zheng Jinxin¹²,Li Duoyun¹²,Deng Qiwen¹²^ORCID,Yu Zhijian¹²

Affiliation:

1. Department of Infectious Diseases and Shenzhen Key Laboratory for Endogenous Infections, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China

2. Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering, Shenzhen University Health Science Center, Shenzhen, China

3. Shenzhen College of International Education, Shenzhen, China

Abstract

The increasing emergence of infectious diseases associated with multidrug-resistant Gram-positive pathogens has raised the urgent need to develop novel antibiotics. GA (15:1) is a natural product derived from Ginkgo biloba and possesses a wide range of bioactivities, including antimicrobial activity.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00991-21

Reference48 articles.

1. Epidemiological and resistance issues in multidrug-resistant staphylococci and enterococci

2. Infections caused by Gram-positive bacteria: a review of the global challenge