Characterizations of the Gut Bacteriome, Mycobiome, and Virome in Patients with Osteoarthritis-Reference-Cited by-同舟云学术

Characterizations of the Gut Bacteriome, Mycobiome, and Virome in Patients with Osteoarthritis

Published:2023-02-14 Issue:1 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Chen Changming¹,Zhang Yue²,Yao Xueming¹,Li Shenghui²,Wang Guangyang³,Huang Ying¹,Yang Yutao¹,Zhang Aiqin²,Liu Can¹,Zhu Dan¹,Li Hufan¹,Yan Qiulong³^ORCID,Ma Wukai¹^ORCID

Affiliation:

1. Department of Rheumatology and Immunology, The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang, China

2. Puensum Genetech Institute, Wuhan, China

3. Department of Microbiology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China

Abstract

The gut microbiome of OA patients was completely altered compared to that in healthy individuals, including 279 differentially abundant bacterial species, 10 fungal species and 627 viral operational taxonomic units (vOTUs). Functional analysis of the gut bacteriome and virome also revealed their functional signatures in relation to OA.

Funder

Scientific Research Project of the Secind Affiliated Hospital of Guizhou University of Traditional Chinese Medicine

贵州省科技厅 | Science and Technology Program of Guizhou Province

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.01711-22

Reference72 articles.

1. Osteoarthritis in the Middle-Aged and Elderly in China: Prevalence and Influencing Factors