Determining the Time of Booster Dose Based on the Half-Life and Neutralization Titers against SARS-CoV-2 Variants of Concern in Fully Vaccinated Individuals-Reference-Cited by-同舟云学术

Determining the Time of Booster Dose Based on the Half-Life and Neutralization Titers against SARS-CoV-2 Variants of Concern in Fully Vaccinated Individuals

Published:2023-08-17 Issue:4 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Dai Yu-Ching¹,Lin Yen-Chia¹,Ching Lauren L.¹²,Tsai Jih-Jin³⁴⁵,Ishikawa Kyle⁶,Tsai Wen-Yang¹²,Chen John J.⁶,Nerurkar Vivek R.¹²,Wang Wei-Kung¹²^ORCID

Affiliation:

1. Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, USA

2. Pacific Center for Emerging Infectious Diseases, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, USA

3. Tropical Medicine Center, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan

4. Division of Infectious Diseases, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan

5. School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

6. Department of Quantitative Health Sciences, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, USA

Abstract

Despite improved understanding of the biology of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), the evolutionary trajectory of the virus is uncertain, and the concern of future antigenically distinct variants remains. Current recommendations for a COVID-19 vaccine booster dose are primarily based on neutralization capacity, effectiveness against circulating variants of concern (VOC), and other host factors.

Funder

City and County of Honolulu

CU | National Cancer Institute, Cairo University

Hawaii Community Foundation

MOHW | Health Promotion Administration, Ministry of Health and Welfare

National Health Research Institutes

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.04081-22

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