Effects of Long-Term Enclosed Environment on Human Health Based on the Analysis of Salivary Microbiota and Cytokines

Author:

Hao Zikai12ORCID,Zhu Yinzhen13,Fu Yuming134,Yang Jianlou13,Meng Chen13,Dong Chen5,Liu Hong134ORCID

Affiliation:

1. Beijing Advanced Innovation Centre for Biomedical Engineering, Beihang University, Beijing, China

2. State Key Laboratory of Software Development Environment, School of Computer Science and Engineering, Beihang University, Beijing, China

3. Institute of Environmental Biology and Life Support Technology, School of Biological Science and Medical Engineering, Beihang University, Beijing, China

4. International Joint Research Center of Aerospace Biotechnology & Medical Engineering, Beihang University, Beijing, China

5. Laboratory of Sport Nutrition and Intelligent Cooking, Shandong Sport University, Jinan, China

Abstract

Long-term exposure to space environments may influence the human microbiome, the human immune system, and the intricate balance between the two, causing impaired immunity and increased disease susceptibility. It was previously believed that the main potential factors of long-term spaceflight on human health were microgravity and radiation.

Funder

Beijing Natural Science Foundation

China Postdoctoral Science Foundation

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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