A Critical Role for p53 during the HPV16 Life Cycle-Reference-Cited by-同舟云学术

A Critical Role for p53 during the HPV16 Life Cycle

Published:2022-06-29 Issue:3 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Fontan Christian T.¹,James Claire D.¹,Prabhakar Apurva T.¹,Bristol Molly L.¹²,Otoa Raymonde¹,Wang Xu¹,Karimi Elmira¹,Rajagopalan Pavithra³,Basu Devraj³⁴,Morgan Iain M.¹²^ORCID

Affiliation:

1. Philips Institute for Oral Health Research, School of Dentistry, Virginia Commonwealth University (VCU), Richmond, Virginia, USA

2. VCU Massey Cancer Center, Richmond, Virginia, USA

3. Department of Otorhinolaryngology, University of Pennsylvania, Philadelphia, Pennsylvania, USA

4. The Wistar Institute Cancer Center, Philadelphia, Pennsylvania, USA

Abstract

Human papillomaviruses are causative agents in around 5% of all cancers. There are currently no antivirals available to combat these infections and cancers, therefore it remains a priority to enhance our understanding of the HPV life cycle.

Funder

HHS | NIH | National Cancer Institute

HHS | NIH | National Institute of Dental and Craniofacial Research

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00681-22

Reference79 articles.

1. Papillomaviruses in the causation of human cancers — a brief historical account

2. HPV-associated head and neck cancer: a virus-related cancer epidemic