Synergistic Antibiofilm Effects of Pseudolaric Acid A Combined with Fluconazole against Candida albicans via Inhibition of Adhesion and Yeast-To-Hypha Transition-Reference-Cited by-同舟云学术

Synergistic Antibiofilm Effects of Pseudolaric Acid A Combined with Fluconazole against Candida albicans via Inhibition of Adhesion and Yeast-To-Hypha Transition

Published:2022-04-27 Issue:2 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Zhu Bin¹,Li Zhen¹,Yin Hongmei¹,Hu Jun¹,Xue Yingjun¹,Zhang Guanyi¹,Zheng Xin¹,Chen Weiqin¹,Hu Xiaobo¹^ORCID

Affiliation:

1. Department of Laboratory Medicine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China

Abstract

Biofilms are the primary cause of antibiotic-resistant candida infections associated with medical implants and devices worldwide. Treating biofilm-associated infections is a challenge for clinicians because these infections are intractable and persistent. Candida albicans readily forms extensive biofilms on the surface of medical implants and mucosa.

Funder

National Natural Science Foundation of China

Longhua Hospital Shanghai University of TCM | Science and Technology Innovation Project of Longhua Hospital

Shanghai Rising-Star Program

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.01478-21

Reference45 articles.

1. Hidden Killers: Human Fungal Infections