H5Nx Viruses Emerged during the Suppression of H5N1 Virus Populations in Poultry-Reference-Cited by-同舟云学术

H5Nx Viruses Emerged during the Suppression of H5N1 Virus Populations in Poultry

Published:2021-10-31 Issue:2 Volume:9 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Li Yao-Tsun¹,Su Yvonne C. F.¹^ORCID,Smith Gavin J. D.¹²³^ORCID

Affiliation:

1. Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore

2. SingHealth Duke-NUS Global Health Institute, SingHealth Duke-NUS Academic Medical Centre, Singapore

3. Duke Global Health Institute, Duke University, Durham, North Carolina, USA

Abstract

A major shift in the ecology of highly pathogenic avian influenza (HPAI) H5 viruses occurred from 2008 to 2014, when viruses with non-N1 neuraminidase genes (termed H5Nx viruses) emerged and caused global H5 virus outbreaks. Here, we demonstrate that nationwide control measures, including vaccination in China, successfully suppressed H5N1 populations in poultry, providing an opportunity for antigenically distinct H5Nx viruses to emerge.

Funder

Ministry of Health -Singapore

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/Spectrum.01309-21

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