Epidemiology and Genetic Characteristics of Carbapenem-Resistant Escherichia coli in Chinese Intensive Care Unit Analyzed by Whole-Genome Sequencing: a Prospective Observational Study-Reference-Cited by-同舟云学术

Epidemiology and Genetic Characteristics of Carbapenem-Resistant Escherichia coli in Chinese Intensive Care Unit Analyzed by Whole-Genome Sequencing: a Prospective Observational Study

Published:2023-04-13 Issue:2 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Ding Ying¹²³^ORCID,Zhuang Hemu⁴²³,Zhou Junxin⁴²³,Xu Lijie¹,Yang Yi⁵,He Jintao⁴²³,Liang Min¹²³,Jia Shicheng⁶,Guo Xiuliu¹²³,Han Xinhong⁴²³,Liu Haiyang⁴²³,Zhang Linghong⁴²³,Jiang Yan⁴²³,Yu Yunsong⁴²³^ORCID

Affiliation:

1. Department of Intensive Care Unit, Sir Run Run Shaw Hospital Qiantang Campus, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China

2. Key Laboratory of Microbial Technology and Bioinformatics of Zhejiang Province, Hangzhou, Zhejiang Province, China

3. Regional Medical Center for National Institute of Respiratory Diseases, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China

4. Department of Infectious Diseases, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China

5. Department of Pharmacy, Sir Run Run Shaw Hospital Xiasha Campus, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China

6. Shantou University Medical College, Shantou, Guangdong Province, China

Abstract

CREC represents a public health threat worldwide, and its colonization precedes or occurs simultaneously with infection; once the colonization rate increases, the infection rate rises sharply. In our hospital, the colonization rate of CREC remained low, and almost all of the CREC isolates detected were ICU acquired.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.04010-22

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