SARS Antibody Testing in Children: Development of Oral Fluid Assays for IgG Measurements-Reference-Cited by-同舟云学术

SARS Antibody Testing in Children: Development of Oral Fluid Assays for IgG Measurements

Published:2022-02-23 Issue:1 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Hoschler Katja¹^ORCID,Ijaz Samreen¹,Andrews Nick²,Ho Sammy¹,Dicks Steve¹³,Jegatheesan Keerthana¹³,Poh John¹,Warrener Lenesha¹,Kankeyan Thivya¹,Baawuah Frances²,Beckmann Joanne⁴,Okike Ifeanichukwu O.⁵,Ahmad Shazaad⁶,Garstang Joanna⁷,Brent Andrew J.⁸⁹,Brent Bernadette⁸⁹,Aiano Felicity²,Brown Kevin E.²,Ramsay Mary E.²,Brown David¹¹⁰,Parry John V.¹,Ladhani Shamez N.²¹¹,Zambon Maria¹

Affiliation:

1. Virus Reference Department, Public Health England, London, United Kingdom

2. Immunisation and Countermeasures Division, Public Health England, London, United Kingdom

3. Microbiology Services Laboratory, NHS Blood and Transplant, Bristol, United Kingdom

4. East London NHS Foundation Trust, London, United Kingdom

5. Derbyshire Healthcare NHS Foundation Trust, Derby, United Kingdom

6. Manchester University NHS Foundation Trust, Manchester, United Kingdom

7. Birmingham Community Healthcare NHS Trust, Aston, United Kingdom

8. Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom

9. University of Oxford, Oxford, United Kingdom

10. Fundação Oswaldo Cruz-Fiocruz, Instituto Oswaldo Cruz, Laboratório de Vírus Respiratórios e do Sarampo, Rio de Janeiro, Rio de Janeiro, Brasil

11. Paediatric Infectious Diseases Research Group, St. George’s University of London, London, United Kingdom

Abstract

We report on the first large-scale assessment of the suitability of oral fluids for detection of SARS-CoV-2 antibody obtained from healthy children attending school. The sample type (gingiva-crevicular fluid, which is a transudate of blood but is not saliva) can be self collected.

Funder

Government of the United Kingdom

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00786-21

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