Genomic Investigation and Successful Containment of an Intermittent Common Source Outbreak of OXA-48-Producing Enterobacter cloacae Related to Hospital Shower Drains

Author:

Nurjadi Dennis1ORCID,Scherrer Martin1,Frank Uwe123,Mutters Nico T.13ORCID,Heininger Alexandra14,Späth Isabel1,Eichel Vanessa M.1,Jabs Jonas13,Probst Katja1,Müller-Tidow Carsten5,Brandt Juliane5,Heeg Klaus1,Boutin Sébastien1

Affiliation:

1. Department of Infectious Diseases, Medical Microbiology and Hygiene, Heidelberg University Hospital, Heidelberg, Germany

2. Institute for Infection Prevention and Hospital Epidemiology, Medical Center, University of Freiburg, Freiburg im Breisgau, Germany

3. Institute for Hygiene and Public Health, Bonn University Hospital, Bonn, Germany

4. Department of Hospital Hygiene, University Medical Center Mannheim, Mannheim, Germany

5. Department of Hematology, Oncology, and Rheumatology, University Hospital Heidelberg, Heidelberg, Germany

Abstract

The hospital water environment can be a reservoir for a multiward outbreak, leading to acquisitions or transmissions of multidrug-resistant organisms in a hospital setting. The majority of Gram-negative bacteria are able to build biofilms and persist in the hospital plumbing system over a long period of time.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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