Concordance between Genotypic and Phenotypic Drug-Resistant Profiles of Shigella Isolates from Taiyuan City, Shanxi Province, China, 2005 to 2016

Author:

Kong Mimi1,Liu Chunmei1,Xu Yang2,Wang Jitao12,Jin Dong13ORCID

Affiliation:

1. Department of Epidemiology, School of Public Health, Shanxi Medical University, Taiyuan City, Shanxi Province, China

2. Department of Microbiology Test, Taiyuan Center for Disease Control and Prevention, Taiyuan City, Shanxi Province, China

3. State Key Laboratory of Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing, China

Abstract

Antimicrobial resistance in Shigella spp. has become a global public health concern. In this study, we identified the antimicrobial susceptibility testing (AST) characteristics based on genomic sequences of 218 Shigella isolates and analyzed the correlation between genotypic and phenotypic antibiotic resistance profiles of Shigella spp., especially for fluoroquinolone, macrolides, and third-generation cephalosporins.

Funder

Basic Research Project of Shanxi Province

Units of Discovery of Unknown Bacteria and Function

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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