Lysis Cassette-Mediated Exoprotein Release in Yersinia entomophaga Is Controlled by a PhoB-Like Regulator-Reference-Cited by-同舟云学术

Lysis Cassette-Mediated Exoprotein Release in Yersinia entomophaga Is Controlled by a PhoB-Like Regulator

Published:2023-04-13 Issue:2 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Schoof Marion¹^ORCID,O’Callaghan Maureen¹^ORCID,Hefer Charles¹^ORCID,Glare Travis R.²^ORCID,Paulson Amber R.³^ORCID,Hurst Mark R. H.¹^ORCID

Affiliation:

1. AgResearch, Resilient Agriculture, Lincoln Research Centre, Lincoln, New Zealand

2. Wine and Molecular Biosciences Dept, Faculty of Agriculture and Life Sciences, Lincoln University, Lincoln, New Zealand

3. British Columbia Ministry of Environment and Climate Change Strategy, Victoria, British Columbia, Canada

Abstract

While theoretical models exist, there is not yet any empirical data that links ALC phage-like lysis cassettes with the release of large macro-molecular toxin complexes, such as Yen-Tc in Gram-negative bacteria. In this study, we demonstrate that the novel Y. entomophaga RoeA activates the production of exoproteins (including Yen-Tc) and the ALC at the transcriptional level.

Funder

Ministry for Business Innovation and Employment

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00364-23

Reference62 articles.

1. Identification of aCampylobacter jejuni-secreted protein required for maximal invasion of host cells

2. Selective Sorting of Cargo Proteins into Bacterial Membrane Vesicles

3. Tracking Proteins Secreted by Bacteria: What's in the Toolbox?

4. Bacterial Secretion Systems: An Overview

5. The Type IX Secretion System Is Required for Virulence of the Fish Pathogen Flavobacterium columnare

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The construction and evaluation of secretory expression engineering bacteria for the trans-Cry3Aa-T-HasA fusion protein against the Monochamus alternatus vector;Frontiers in Cellular and Infection Microbiology;2024-02-23

2. Stepwise assembly and release of Tc toxins from Yersinia entomophaga;Nature Microbiology;2024-02-05

3. Yersinia entomophaga Tc toxin is released by T10SS-dependent lysis of specialized cell subpopulations;Nature Microbiology;2024-01-18

4. Serratia‐based toxin cluster elements are associated with a type I fimbria;MicrobiologyOpen;2024-01-02