Selection of Ideal Reference Genes for Gene Expression Analysis in COVID-19 and Mucormycosis-Reference-Cited by-同舟云学术

Selection of Ideal Reference Genes for Gene Expression Analysis in COVID-19 and Mucormycosis

Published:2022-12-21 Issue:6 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Kumar Sunil¹,Ahmad Ayaan¹,Kushwaha Namrata¹,Shokeen Niti¹,Negi Sheetal¹,Gautam Kamini¹,Singh Anup²,Tiwari Pavan³,Garg Rakesh⁴,Agarwal Richa⁴,Mohan Anant³,Trikha Anjan⁴,Thakar Alok²,Saini Vikram¹⁵^ORCID

Affiliation:

1. Laboratory of Infection Biology and Translational Research, Department of Biotechnology, All India Institute of Medical Sciences, New Delhi, India

2. Department of Otorhinolaryngology-Head & Neck Surgery, All India Institute of Medical Sciences (AIIMS), New Delhi, India

3. Department of Pulmonary Medicine and Sleep Disorders, All India Institute of Medical Sciences (AIIMS), New Delhi, India

4. Department of Onco-Anesthesiology, Intensive Care, Pain and Palliative Medicine, All India Institute of Medical Sciences (AIIMS), New Delhi, India

5. Biosafety Laboratory-3, Centralized Core Research Facility (CCRF), All India Institute of Medical Sciences (AIIMS), New Delhi, India

Abstract

Gene expression studies are critical to develop new diagnostics, therapeutics, and prognostic modalities. However, accurate determination of expression requires data normalization with a reference gene, whose expression does not vary across different disease stages.

Funder

All-India Institute of Medical Sciences

Department of Biotechnology, Ministry of Science and Technology, India

DST | Science and Engineering Research Board

Defence Research and Development Organisation

MOHFW | Department of Health Research, India

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.01656-22