Single Nucleotide Polymorphism-Based Real-Time PCR Screening Assay for Rapid Tracking of Bacterial Infection Clusters To Complement Whole-Genome Sequencing Efforts during Outbreak Investigations-Reference-Cited by-同舟云学术

Single Nucleotide Polymorphism-Based Real-Time PCR Screening Assay for Rapid Tracking of Bacterial Infection Clusters To Complement Whole-Genome Sequencing Efforts during Outbreak Investigations

Published:2022-12-21 Issue:6 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Treffon Janina¹,Heppner Bianca¹,Eismann Julia²,Bothe Julia²,Omengo Birgit²,Mellmann Alexander¹^ORCID

Affiliation:

1. University Hospital Münster, Institute of Hygiene, Münster, Germany

2. inno-train Diagnostik GmbH, Kronberg, Germany

Abstract

Infection clusters of multidrug-resistant bacteria threaten medical facilities worldwide and cause immense health care costs. In recent years, whole-genome sequencing (WGS) has been increasingly applied to detect and to further control bacterial clusters.

Funder

Bundesministerium für Bildung und Forschung

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.03036-22

Reference53 articles.

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2. WHO. 2021. Global antimicrobial resistance and use surveillance system (GLASS) report 2021. World Health Organization, Geneva, Switzerland.

3. The impact of hospital-acquired infections with multidrug-resistant bacteria in an oncology intensive care unit

4. Cost-Analysis of Seven Nosocomial Outbreaks in an Academic Hospital

5. The rising problem of antimicrobial resistance in the intensive care unit

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