A Novel Robust Method Mimicking Human Substratum To Dissect the Heterogeneity of Candida auris Biofilm Formation-Reference-Cited by-同舟云学术

A Novel Robust Method Mimicking Human Substratum To Dissect the Heterogeneity of Candida auris Biofilm Formation

Published:2023-08-17 Issue:4 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Biswas Biswambhar¹,Rana Aishwarya¹,Gupta Nidhi¹,Gupta Ishaan²^ORCID,Puria Rekha³,Thakur Anil¹^ORCID

Affiliation:

1. Laboratory of Protein Translation and Fungal Pathogenesis, Regional Centre for Biotechnology, Faridabad, Haryana, India

2. Department of Biochemical Engineering and Biotechnology, Indian Institute of Technology Delhi, Delhi, India

3. School of Biotechnology, Gautam Buddha University, Greater Noida, Uttar Pradesh, India

Abstract

Heterogeneity is seen when multidrug-resistant C. auris biofilm is cultured using different reported methods. Biofilm formed on the gelatin surface mimics the condition of a host environment that has multilayers and EPS.

Funder

DST | Science and Engineering Research Board

Department of Biotechnology, Ministry of Science and Technology, India

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00892-23

Reference35 articles.

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2. Centers for Disease Control and Prevention (CDC). 2023. Tracking Candida auris . https://www.cdc.gov/fungal/candida-auris/tracking-c-auris.html.

3. Investigation of the First Seven Reported Cases ofCandida auris,a Globally Emerging Invasive, Multidrug-Resistant Fungus — United States, May 2013–August 2016

4. Post-transcriptional and translational control of the morphology and virulence in human fungal pathogens

5. Simultaneous Emergence of Multidrug-ResistantCandida aurison 3 Continents Confirmed by Whole-Genome Sequencing and Epidemiological Analyses

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