Large Comparative Analyses of Primate Body Site Microbiomes Indicate that the Oral Microbiome Is Unique among All Body Sites and Conserved among Nonhuman Primates

Author:

Asangba Abigail E.12ORCID,Mugisha Lawrence34,Rukundo Joshua5,Lewis Rebecca J.6,Halajian Ali7,Cortés-Ortiz Liliana8,Junge Randall E.9,Irwin Mitchell T.10,Karlson Johan11,Perkin Andrew11,Watsa Mrinalini1213,Erkenswick Gideon1314,Bales Karen L.15,Patton Dorothy L.16,Jasinska Anna J.1718ORCID,Fernandez-Duque Eduardo19ORCID,Leigh Steven R.220,Stumpf Rebecca M.1212223ORCID

Affiliation:

1. Department of Anthropology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA

2. Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA

3. Ecohealth Research Group, Conservation & Ecosystem Health Alliance (CEHA), Kampala, Uganda

4. Department of Wildlife & Aquatic Animal Resources, College of Veterinary Medicine, Animal Resources & Biosecurity (COVAB), Makerere University, Kampala, Uganda

5. Chimpanzee Sanctuary and Wildlife Conservation (Chimpanzee Trust), Ngamba Island, Uganda

6. Department of Anthropology, University of Texas at Austin, Austin, Texas, USA

7. Research Administration and Development, University of Limpopo, Sovenga, South Africa

8. Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, Michigan, USA

9. Columbus Zoo and Aquarium, Powell, Ohio, USA

10. Department of Anthropology, Northern Illinois University, DeKalb, Illinois, USA

11. Tanzania Forest Conservation Group and Nocturnal Primate Research Group, Dar es Salaam, Tanzania

12. San Diego Zoo Wildlife Alliance, San Diego, California, USA

13. Field Projects International, Escondido, California, USA

14. Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA

15. Department of Psychology, University of California Davis, Davis, California, USA

16. Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington, USA

17. Division of Infectious Diseases, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA

18. Department of Molecular Genetics, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland

19. Department of Anthropology, Yale University, New Haven, Connecticut, USA

20. Department of Anthropology, University of Colorado—Boulder, Boulder, Colorado, USA

21. Kanyanchu River Chimpanzee Project and Research Collaborative, Bigodi, Uganda

22. Program in Ecology, Evolution and Conservation Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA

23. Notre Dame Institute for Advanced Study, University of Notre Dame, Notre Dame, Indiana, USA

Abstract

The microbiome is critical to host health and disease, but much remains unknown about the determinants, levels, and evolution of host-microbial diversity. The relationship between hosts and their associated microbes is complex.

Funder

HHS | National Institutes of Health

National Science Foundation

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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