Development of an Inactivated H7N9 Subtype Avian Influenza Serological DIVA Vaccine Using the Chimeric HA Epitope Approach-Reference-Cited by-同舟云学术

Development of an Inactivated H7N9 Subtype Avian Influenza Serological DIVA Vaccine Using the Chimeric HA Epitope Approach

Published:2021-10-31 Issue:2 Volume:9 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Sun Zhihao¹²³,Wang Qiuxia¹²³,Li Gang¹²³,Li Jingzhi⁴,Chen Sujuan¹²³,Qin Tao¹²³,Ma Hongwei⁴,Peng Daxin¹²³⁵^ORCID,Liu Xiufan¹²³

Affiliation:

1. College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, China

2. Jiangsu Co-Innovation Center for the Prevention and Control of Important Animal Infectious Disease and Zoonoses, Yangzhou, Jiangsu, China

3. Jiangsu Research Centre of Engineering and Technology for Prevention and Control of Poultry Disease, Yangzhou, Jiangsu, China

4. Suzhou Institute of Nano-tech and Nano-bionics, Chinese Academy of Sciences, Suzhou, Jiangsu, China

5. Joint International Research Laboratory of Agriculture and Agri-Product Safety, The Ministry of Education of China, Yangzhou, Jiangsu, China

Abstract

DIVA vaccine is a useful tool for eradicating avian influenza, especially for highly pathogenic avian influenza. Several different DIVA strategies have been proposed for avian influenza inactivated whole-virus vaccine, involving the neuraminidase (NA), nonstructural protein 1 (NS1), matrix protein 2 ectodomain (M2e), or HA2 gene.

Funder

MOST | National Key Research and Development Program of China

Priority Academic Program Development of Jiangsu Higher Education Institutions

Jiangsu provincial natural science fund for excellent young scholars

High-level talent support plan of Yangzhou University

Key R&D project of Jiangsu province

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/Spectrum.00687-21