Structural and Functional Analysis of SsaV Cytoplasmic Domain and Variable Linker States in the Context of the InvA-SsaV Chimeric Protein-Reference-Cited by-同舟云学术

Structural and Functional Analysis of SsaV Cytoplasmic Domain and Variable Linker States in the Context of the InvA-SsaV Chimeric Protein

Published:2021-12-22 Issue:3 Volume:9 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Xu Jinghua¹,Wang Jiuqing¹,Liu Aijun²,Zhang Yanqing²,Gao Xiang¹³^ORCID

Affiliation:

1. State Key Laboratory of Microbial Technology, Shandong University, Qingdao, China

2. Shanghai Fifth People's Hospital and Shanghai Key Laboratory of Medical Epigenetics, International Co-laboratory of Medical Epigenetics and Metabolism (Ministry of Science and Technology), Institutes of Biomedical Sciences, Fudan University, Shanghai, China

3. School of Life Sciences, Shandong University, Qingdao, China

Abstract

Type III secretion system (T3SS) is a multicomponent nanomachine and a critical virulence factor for a wide range of Gram-negative bacterial pathogens. It can deliver numbers of effectors into the host cell to facilitate the bacterial host infection.

Funder

MOST | National Key Research and Development Program of China

Natural Science Foundation of Shandong Province

Taishan Young Scholars program

Fudan University

the youth interdisciplinary innovative research group of shandong university

National Natural Science Foundation of China

Shanghai Rising-Star Program

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology