Transmission of NDM-5-Producing and OXA-48-Producing Escherichia coli Sequence Type 648 by International Visitors without Previous Medical Exposure

Author:

Harada Sohei12ORCID,Suzuki Masahiro3ORCID,Sasaki Toshiharu23,Sakurai Aki23ORCID,Inaba Masato2,Takuya Hosoda4,Wakuda Mitsutaka5,Doi Yohei236ORCID

Affiliation:

1. Department of Infection Control and Prevention, The University of Tokyo Hospital, Hongo, Bunkyo-ku, Tokyo, Japan

2. Department of Infectious Diseases, Fujita Health University School of Medicine, Toyoake, Aichi, Japan

3. Department of Microbiology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan

4. Department of Joint Research Laboratory of Clinical Medicine, Fujita Health University Okazaki Medical Center, Okazaki, Aichi, Japan

5. Department of Joint Research Laboratory of Clinical Medicine, Fujita Health University Hospital, Toyoake, Aichi, Japan

6. Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

Abstract

Although patients with history of international hospitalization are often subject to screening for multidrug-resistant organisms, it is unclear whether patients who reside in countries where carbapenemase-producing Enterobacterales (CPE) is endemic but have no history of local hospitalization contribute to the transmission of CPE. In this study, NDM-5-producing and OXA-48-producing Escherichia coli sequence type (ST) 648, a recently recognized high-risk, multidrug-resistant clone, were detected from two overseas visitors without previous medical exposure.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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