Effect of Intragenomic Sequence Heterogeneity among Multiple 16S rRNA Genes on Species Identification of Elizabethkingia

Author:

Lin Jiun-Nong1234ORCID,Lai Chung-Hsu34,Lin Shang-Yi5ORCID,Lee Ching-Chi6ORCID,Lee Nan-Yao78,Liu Po-Yu9,Yang Chih-Hui10,Huang Yi-Han1

Affiliation:

1. College of Medical Science and Technology, I-Shou University, Kaohsiung, Taiwan

2. Department of Critical Care Medicine, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan

3. Division of Infectious Diseases, Department of Internal Medicine, E-Da Hospital, I-Shou University, Kaohsiung, Taiwan

4. School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan

5. Division of Infectious Diseases, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan

6. Clinical Medicine Research Center, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan

7. Division of Infectious Diseases, Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan

8. School of Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan

9. Division of Infectious Diseases, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan

10. Department of Biological Science and Technology, Meiho University, Pingtung, Taiwan

Abstract

Incorrect identification of bacterial species would influence the epidemiology and clinical analysis of patients infected with Elizabethkingia . The results of the present study suggest that 16S rRNA gene sequencing should not be considered the gold standard for the accurate identification of Elizabethkingia species.

Funder

Ministry of Science and Technology, Taiwan

E-Da Hospital

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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