Human Claudin-Derived Peptides Block the Membrane Fusion Process of Zika Virus and Are Broad Flavivirus Inhibitors-Reference-Cited by-同舟云学术

Human Claudin-Derived Peptides Block the Membrane Fusion Process of Zika Virus and Are Broad Flavivirus Inhibitors

Published:2022-10-26 Issue:5 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Zoladek Jim¹^ORCID,Burlaud-Gaillard Julien²³,Chazal Maxime⁴,Desgraupes Sophie¹,Jeannin Patricia¹,Gessain Antoine¹,Pardigon Nathalie⁵,Hubert Mathieu⁶,Roingeard Philippe²³,Jouvenet Nolwenn⁴^ORCID,Afonso Philippe V.¹^ORCID

Affiliation:

1. Unité Épidémiologie et Physiopathologie des Virus Oncogènes, Institut Pasteur, Université Paris Cité, CNRS UMR 3569, Paris, France

2. Inserm U1259 MAVIVH, Université de Tours and CHRU de Tours, Tours, France

3. Plate-Forme IBiSA de Microscopie Electronique, Université de Tours and CHRU de Tours, Tours, France

4. Unité Signalisation Antivirale, Institut Pasteur, Université Paris Cité, CNRS UMR 3569, Paris, France

5. Groupe Arbovirus, Unité Environnement et Risques Infectieux, Institut Pasteur, Université Paris Cité, Paris, France

6. Unité Virus et Immunité, Institut Pasteur, Université Paris Cité, CNRS UMR 3569, Paris, France

Abstract

Zika virus (ZIKV) is a flavivirus transmitted by mosquito bites that have spread to the Pacific Islands and the Americas over the past decade. The infection remains asymptomatic in most cases but can cause severe neurological disorders.

Funder

Pasteur Fiocruz

Agence Nationale de la Recherche

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.02989-22

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1. The continued threat of emerging flaviviruses

2. Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study