Susceptibility of Ugandan Plasmodium falciparum Isolates to the Antimalarial Drug Pipeline-Reference-Cited by-同舟云学术

Susceptibility of Ugandan Plasmodium falciparum Isolates to the Antimalarial Drug Pipeline

Published:2023-06-15 Issue:3 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Kreutzfeld Oriana¹^ORCID,Tumwebaze Patrick K.²,Okitwi Martin²,Orena Stephen²,Byaruhanga Oswald²,Katairo Thomas²,Conrad Melissa D.¹^ORCID,Rasmussen Stephanie A.³,Legac Jennifer¹,Aydemir Ozkan⁴,Giesbrecht David⁵,Forte Barbara⁶,Campbell Peter⁶,Smith Alasdair⁶,Kano Hiroki⁷,Nsobya Samuel L.²,Blasco Benjamin⁸,Duffey Maelle⁸,Bailey Jeffrey A.⁵,Cooper Roland A.³^ORCID,Rosenthal Philip J.¹^ORCID

Affiliation:

1. University of California, San Francisco, San Francisco, California, USA

2. Infectious Diseases Research Collaboration, Kampala, Uganda

3. Dominican University of California, San Rafael, California, USA

4. Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA

5. Brown University, Providence, Rhode Island, USA

6. Wellcome Centre for Anti-Infectives Research, Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee, United Kingdom

7. Mitsubishi Tanabe Pharma Corporation, Yokohama, Japan

8. Medicines for Malaria Venture, Geneva, Switzerland

Abstract

Drug resistance necessitates the development of new antimalarial drugs. It is important to assess the activities of compounds under development against parasites now causing disease in Africa, where most malaria cases occur, and to determine if mutations in these parasites may limit the efficacies of new agents.

Funder

National Institute of Health

Medicines for Malaria Venture

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.05236-22

Reference57 articles.

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2. Evidence of Artemisinin-Resistant Malaria in Africa

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