Acinetobacter nosocomialis Causes as Severe Disease as Acinetobacter baumannii in Northeast Thailand: Underestimated Role of A. nosocomialis in Infection

Author:

Nithichanon Arnone12,Kewcharoenwong Chidchamai13,Da-oh Hudadini1,Surajinda Sirithorn1,Khongmee Aranya3,Koosakunwat Surathinee4,Wren Brendan W.5ORCID,Stabler Richard A.5ORCID,Brown Jeremy S.6,Lertmemongkolchai Ganjana13ORCID

Affiliation:

1. Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand

2. Research and Diagnostic Center for Emerging Infectious Diseases (RCEID), Department of Microbiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand

3. Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand

4. Department of Medicine, Nakhon Phanom Hospital, Nakhon Phanom, Thailand

5. Department of Infection Biology, London School of Hygiene and Tropical Medicine, Infectious and Tropical Disease, London, United Kingdom

6. Centre for Inflammation and Tissue Repair, UCL Respiratory, London, United Kingdom

Abstract

Bacterial infections by Acinetobacter species are global threats due to their severity and high levels of antibiotic resistance. A. baumannii is the most common pathogen in the genus; however, infection by A. nosocomialis has also been widely reported but is thought to be less severe. In this study, we have prospectively investigated 48 reported cases of A. baumannii infection in Northeast Thailand, and characterized the serological responses to infection.

Funder

UKRI | Medical Research Council

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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