Pf4 Phage Variant Infection Reduces Virulence-Associated Traits in <i>Pseudomonas aeruginosa</i>-Reference-Cited by-同舟云学术

Pf4 Phage Variant Infection Reduces Virulence-Associated Traits in Pseudomonas aeruginosa

Published:2022-10-26 Issue:5 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Tortuel Damien¹²,Tahrioui Ali¹²,David Audrey¹²,Cambronel Mélyssa¹²,Nilly Flore¹²,Clamens Thomas³,Maillot Olivier¹²,Barreau Magalie¹²,Feuilloley Marc G. J.¹²^ORCID,Lesouhaitier Olivier¹²,Filloux Alain³^ORCID,Bouffartigues Emeline¹²^ORCID,Cornelis Pierre¹²⁴,Chevalier Sylvie¹²^ORCID

Affiliation:

1. Unité de Recherche Communication Bactérienne et Stratégies Anti-infectieuses, CBSA UR4312, Université de Rouen Normandie, Évreux, France

2. Normandie Université, Fédération de Recherche SéSAD, Université de Rouen Normandie, Rouen, France

3. MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College London, London, United Kingdom

4. Laboratorium Microbiologie, Vrije Universiteit Brussel, Brussels, Belgium

Abstract

Filamentous bacteriophages can become superinfective and infect P. aeruginosa , even though they are inserted in the genome as lysogens. Despite this productive infection, growth of the host is only mildly affected, allowing the study of the interaction between the phage and the host, which is not possible in the case of lytic phages killing rapidly their host.

Funder

EC | European Regional Development Fund

Ministère de l'Enseignement Supérieur et de la Recherche Scientifique

Région Normandie

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.01548-22

Reference128 articles.

1. Lung Infections Associated with Cystic Fibrosis