Monitoring SARS-CoV-2 Infection Using a Double Reporter-Expressing Virus-Reference-Cited by-同舟云学术

Monitoring SARS-CoV-2 Infection Using a Double Reporter-Expressing Virus

Published:2022-10-26 Issue:5 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Chiem Kevin¹,Park Jun-Gyu¹,Morales Vasquez Desarey¹,Plemper Richard K.²,Torrelles Jordi B.¹,Kobie James J.³,Walter Mark R.⁴,Ye Chengjin¹^ORCID,Martinez-Sobrido Luis¹^ORCID

Affiliation:

1. Texas Biomedical Research Institute, San Antonio, Texas, USA

2. Center for Translational Antiviral Research, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia, USA

3. Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, Alabama, USA

4. Department of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama, USA

Abstract

Despite the availability of vaccines and antivirals, the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to ravage health care institutions worldwide. Previously, we generated replication-competent recombinant (r)SARS-CoV-2 expressing fluorescent or luciferase reporter proteins to track viral infection in vitro and/or in vivo .

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.02379-22

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