Single-Cell, High-Content Microscopy Analysis of BK Polyomavirus Infection

Author:

Procario Megan C.1ORCID,Sexton Jonathan Z.234ORCID,Halligan Benjamin S.2ORCID,Imperiale Michael J.15ORCID

Affiliation:

1. Department of Microbiology and Immunology, Medical School, University of Michigan, Ann Arbor, Michigan, USA

2. Department of Internal Medicine, Medical School, University of Michigan, Ann Arbor, Michigan, USA

3. Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, Michigan, USA

4. Center for Drug Repurposing, University of Michigan, Ann Arbor, Michigan, USA

5. Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA

Abstract

BK polyomavirus (BKPyV) is a human pathogen that infects nearly everyone by adulthood and persists throughout a person’s life. Only people with significant immune suppression develop disease from the virus, however.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

UM | Medical School, University of Michigan

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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