Aneuploidy Formation in the Filamentous Fungus Aspergillus flavus in Response to Azole Stress-Reference-Cited by-同舟云学术

Aneuploidy Formation in the Filamentous Fungus Aspergillus flavus in Response to Azole Stress

Published:2023-08-17 Issue:4 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Barda Omer¹^ORCID,Sadhasivam Sudharsan¹,Gong Di¹,Doron-Faigenboim Adi²,Zakin Varda¹,Drott Milton T.³,Sionov Edward¹^ORCID

Affiliation:

1. Department of Food Sciences, Institute of Postharvest and Food Sciences, Agricultural Research Organization, Volcani Center, Rishon LeZion, Israel

2. Department of Vegetable and Field Crops, Institute of Plant Sciences, Agricultural Research Organization, Volcani Center, Rishon LeZion, Israel

3. Cereal Disease Laboratory, USDA-ARS, St. Paul, Minnesota, USA

Abstract

Fungal pathogens cause human disease and threaten global food security by contaminating crops with toxins (mycotoxins). Aspergillus flavus is an opportunistic mycotoxigenic fungus that causes invasive and noninvasive aspergillosis, diseases with high rates of mortality in immunocompromised individuals. Additionally, this fungus contaminates most major crops with the notorious carcinogen, aflatoxin.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.04339-22

Reference26 articles.

1. Voriconazole: The Newest Triazole Antifungal Agent

2. Clinical implications of globally emerging azole resistance in Aspergillus fumigatus

3. Frequency and Evolution of Azole Resistance inAspergillus fumigatusAssociated with Treatment Failure1

4. Population genomics confirms acquisition of drug-resistant Aspergillus fumigatus infection by humans from the environment

5. Change in the clinical antifungal sensitivity profile of Aspergillus flavus induced by azole and a benzimidazole fungicide exposure

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