Epstein-Barr Virus Regulates Endothelin-1 Expression through the ERK/FOXO1 Pathway in EBV-Associated Gastric Cancer

Author:

Liu Wen1,Zhang Qianqian1,Zhang Yan12,Sun Lingling3,Xiao Hua1,Luo Bing1ORCID

Affiliation:

1. Department of Pathogenic Biology, School of Basic Medicine, Qingdao University, Qingdao, China

2. Department of Clinical Laboratory, Central Hospital of Zibo, Zibo, China

3. Department of Pathology, Affiliated Hospital of Qingdao University, Qingdao, China

Abstract

The relationship between Epstein-Barr virus and gastric cancer has been relatively clear. However, there are still many unresolved mechanisms of the virus in tumorigenesis.

Funder

Natural Science Foundation of Shandong Province

Qingdao Municipal Science and Technology Bureau

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Reference32 articles.

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2. Methylation of the 5' CpG island of the endothelin B receptor gene is common in human prostate cancer;Nelson JB;Cancer Res,1997

3. Role of endothelin a receptor in colon cancer metastasis: In vitro and in vivo evidence

4. Detection of Big endothelin-1 in peripheral blood of patients with gastric carcinoma and precarcinomatous condition;Chen W;Laboratory Medicine,2007

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