Large-Scale Genomic Epidemiology of Klebsiella pneumoniae Identified Clone Divergence with Hypervirulent Plus Antimicrobial-Resistant Characteristics Causing Within-Ward Strain Transmissions-Reference-Cited by-同舟云学术

Large-Scale Genomic Epidemiology of Klebsiella pneumoniae Identified Clone Divergence with Hypervirulent Plus Antimicrobial-Resistant Characteristics Causing Within-Ward Strain Transmissions

Published:2022-04-27 Issue:2 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Pei Na¹²^ORCID,Li Yanming³,Liu Chunjiao¹⁴^ORCID,Jian Zijuan³,Liang Tianzhu¹⁴,Zhong Yiming³,Sun Wanying¹,He Jingxuan³,Cheng Xinyi¹,Li Hongling³,Lei Xiaole¹,Liu Xin¹,Deng Ziqing¹⁴,Liu Qingxia³,Chen Xia³,Yan Qun³,Kristiansen Karsten¹²,Li Junhua¹⁴,Liu Wenen³⁵^ORCID

Affiliation:

1. BGI-Shenzhen, Shenzhen, Guangdong, China

2. Laboratory of Genomics and Molecular Biomedicine, Department of Biology, University of Copenhagen, Copenhagen, Denmark

3. Department of Clinical Laboratory, Xiangya Hospital, Central South University, Changsha, Hunan, China

4. Shenzhen Key Laboratory of Unknown Pathogen Identification, Shenzhen, Guangdong, China

5. National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Changsha, Hunan, China

Abstract

The convergence of AMR and acquired virulence posing higher risks to the public is a focusing point. With sufficient genomes and genotypes, we successfully identify the convergence in two subclones, the previously reported CG11-KL64, and the newly reported CG25 cluster 1.

Funder

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.02698-21

Reference35 articles.

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3. Hypervirulent Klebsiella pneumoniae