Diagnostic Performance and Tolerability of Saliva and Nasopharyngeal Swab Specimens in the Detection of SARS-CoV-2 by RT-PCR

Author:

Ahti Jaakko12ORCID,Österback Riikka34,Keskitalo Anniina34,Mokkala Kati5,Vidbäck Siina5,Veikkolainen Ville5,Vuorinen Tytti34,Peltola Ville12,Hakanen Antti J.34,Waris Matti34,Laine Miia34ORCID

Affiliation:

1. Department of Paediatrics and Adolescent Medicine, University of Turku, Turku, Finland

2. Department of Paediatrics and Adolescent Medicine, Turku University Hospital, Turku, Finland

3. Department of Clinical Microbiology, Turku University Hospital, Turku, Finland

4. Institute of Biomedicine, University of Turku, Turku, Finland

5. Wallac Oy, PerkinElmer, Turku, Finland

Abstract

The extensive testing of SARS-CoV-2 is vital in controlling the spread of COVID-19. The reference standard for specimen collection is a nasopharyngeal swab (NPS).

Funder

Wallac Oy, PerkinElmer. Funding received by the institution (Turku University Hospital).

Satakunta Hospital District, Pori, Finland

Paulon Säätiö

Maud Kuistilan Muistosäätiö

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Reference36 articles.

1. A Novel Coronavirus from Patients with Pneumonia in China, 2019

2. World Health Organization. 2021. Recommendations for national SARS-CoV-2 testing strategies and diagnostic capacities: interim guidance 25 June 2021. https://apps.who.int/iris/handle/10665/342002.

3. Diagnostic testing for SARS-CoV-2;World Health Organization;Interim Guidance,2020

4. Complications of nasal and pharyngeal swabs: a relevant challenge of the COVID-19 pandemic?

5. Complications of COVID-19 Nasopharyngeal Swab Test

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