Altered Fecal Microbiome and Correlations of the Metabolome with Plasma Metabolites in Dairy Cows with Left Displaced Abomasum

Author:

Luo Zhengzhong1,Yong Kang23,Luo Qiao1,Du Zhenlong1,Ma Li1,Huang Yixin4,Zhou Tao15,Yao Xueping1,Shen Liuhong1,Yu Shumin1ORCID,Deng Junliang1,Ren Zhihua1,Zhang Yong3,Yan Zuoting5,Zuo Zhicai1ORCID,Cao Suizhong1ORCID

Affiliation:

1. Department of Clinical Veterinary Medicine, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China

2. Department of Animal Husbandry & Veterinary Medicine, College of Animal Science and Technology, Chongqing Three Gorges Vocational College, Chongqing, China

3. Department of Clinical Veterinary Medicine, College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, China

4. Institute of Biodiversity, Animal Health & Comparative Medicine, College of Medical, Veterinary & Life Sciences, University of Glasgow, Glasgow, United Kingdom

5. Lanzhou Institute of Animal Husbandry and Veterinary Pharmaceutical, Chinese Academy of Agricultural Sciences, Lanzhou, China

Abstract

LDA is a major contributor to economic losses in the dairy industry worldwide; however, the mechanisms associated with the metabolic changes in LDA remain unclear. Most previous studies have focused on the rumen microbiota in terms of understanding the contributors to the productivity and health of dairy cows; this study further sheds light on the relevance of the lower gut microbiota and its associated metabolites in mediating the development of LDA.

Funder

China Agricultural Research System of MOF and MARA

Ganshu Province Guided Science and Technology Innovation Project

Key Research and Development Program Supported by the Department of Science and Technology of Ganshu Province

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Reference60 articles.

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