Genomic Basis of Occurrence of Cryptic Resistance among Oxacillin- and Cefoxitin-Susceptible <i>mecA</i> -Positive Staphylococcus aureus-Reference-Cited by-同舟云学术

Genomic Basis of Occurrence of Cryptic Resistance among Oxacillin- and Cefoxitin-Susceptible mecA -Positive Staphylococcus aureus

Published:2022-06-29 Issue:3 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Liang Bingshao¹,Xiong Zhile¹,Liang Zhuwei¹,Zhang Chao¹,Cai Hao¹,Long Yan¹,Gao Fei¹,Wang Jielin¹,Deng Qiulian¹,Zhong Huamin¹,Xie Yongqiang¹,Huang Lianfen¹,Gong Sitang²,Zhou Zhenwen³^ORCID

Affiliation:

1. Clinical Laboratory, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, People’s Republic of China

2. Department of Gastroenterology, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, People’s Republic of China

3. Clinical Laboratory, Longgang District Maternity and Child Healthcare Hospital, Shenzhen, People’s Republic of China

Abstract

The oxacillin- and cefoxitin-susceptible mecA -positive Staphylococcus aureus is a novel type of “stealth” methicillin-resistant S. aureus (MRSA), which is difficult to be detected using conventional methods. To investigate the genomic basis of their occurrence, we sequenced the whole genome of two previously recovered oxacillin- and cefoxitin-susceptible mecA -positive MRSA isolates from breast abscesses in a lactating woman and a nasal swab of a healthy student in Guangzhou.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Guangdong Science and Technology Department

Guangzhou Municipal Health and Family Planning Commission

Bureau of Science and Information Technology of Guangzhou Municipality | Guangzhou Municipal Science and Technology Project

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00291-22

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