Identifying Bacterial Airways Infection in Stable Severe Asthma Using Oxford Nanopore Sequencing Technologies-Reference-Cited by-同舟云学术

Identifying Bacterial Airways Infection in Stable Severe Asthma Using Oxford Nanopore Sequencing Technologies

Published:2022-04-27 Issue:2 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Jabeen Maisha F.¹²^ORCID,Sanderson Nicholas D.³²,Foster Dona³,Crook Derrick W.³²,Cane Jennifer L.¹²,Borg Catherine¹²,Connolly Clare¹²,Thulborn Samantha¹²,Pavord Ian D.¹²,Klenerman Paul⁴,Street Teresa L.³²^ORCID,Hinks Timothy S. C.¹²^ORCID

Affiliation:

1. Respiratory Medicine Unit, Experimental Medicine Division, Nuffield Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom

2. National Institute for Health Research Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, United Kingdom

3. Nuffield Department of Clinical Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom

4. Peter Medawar Building for Pathogen Research and Translational Gastroenterology Unit, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom

Abstract

The human airways were once thought sterile in health. Now metagenomic techniques suggest bacteria may be present, but their role in asthma is not understood.

Funder

Wellcome Trust

NIHR | NIHR Oxford Biomedical Research Centre

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.02279-21

Reference41 articles.

1. The Effects of Airway Microbiome on Corticosteroid Responsiveness in Asthma

2. Airway dysbiosis: Haemophilus influenzae and Tropheryma in poorly controlled asthma