In Vitro Susceptibilities of Worldwide Isolates of Intrapulmonary Aspergillus Species and Important Candida Species in Sterile Body Sites against Important Antifungals: Data from the Antimicrobial Testing Leadership and Surveillance Program, 2017–2020

Author:

Jean Shio-Shin123,Yang Hung-Jen4,Hsieh Po-Chuen2,Huang Yu-Tsung56,Ko Wen-Chien7,Hsueh Po-Ren589106ORCID

Affiliation:

1. Department of Internal Medicine, Min-Sheng General Hospital, Taoyuan, Taiwan

2. Department of Pharmacy, College of Pharmacy and Health Care, Tajen University, Pingtung, Taiwan

3. Department of Critical Care Medicine, Min-Sheng General Hospital, Taoyuan, Taiwan

4. Department of Family Medicine, Min-Sheng General Hospital, Taoyuan, Taiwan

5. Department of Laboratory Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan

6. Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan

7. Department of Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan

8. Department of Laboratory Medicine, China Medical University Hospital, China Medical University, Taichung, Taiwan

9. School of Medicine, China Medical University, Taichung, Taiwan

10. Ph.D Program for Aging, School of Medicine, China Medical University, Taichung, Taiwan

Abstract

In addition to monitoring the antifungal susceptibilities of clinically important fungi, reviewing the PK/PD indices and the clinical therapy experience of antifungals under evaluation are important to guide an appropriate antifungal prescription. The efficacies of liposomal amphotericin B complex and anidulafungin for the treatment of pulmonary aspergillosis caused by different Aspergillus species need to be periodically evaluated in the future.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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