Novel Antifungal Activity of Q-Griffithsin, a Broad-Spectrum Antiviral Lectin-Reference-Cited by-同舟云学术

Novel Antifungal Activity of Q-Griffithsin, a Broad-Spectrum Antiviral Lectin

Published:2021-10-31 Issue:2 Volume:9 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Nabeta Henry W.¹²^ORCID,Kouokam Joseph C.³,Lasnik Amanda B.²,Fuqua Joshua L.³²,Palmer Kenneth E.³²

Affiliation:

1. Department of Microbiology and Immunology, School of Medicine, University of Louisville, Louisville, Kentucky, USA

2. Center for Predictive Medicine for Biodefense and Emerging Infectious Diseases, University of Louisville, Louisville, Kentucky, USA

3. Department of Pharmacology and Toxicology, School of Medicine, University of Louisville, Louisville, Kentucky, USA

Abstract

Fungal infections contribute to morbidity and mortality annually, and the number of organisms that are nonresponsive to the current available drug regimens are on the rise. There is a need to develop new agents to counter these infections and to add to the limited arsenal available to treat fungal infections.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/Spectrum.00957-21

Reference86 articles.

1. Multidrug-Resistant Candida: Epidemiology, Molecular Mechanisms, and Treatment

2. Frequent detection of ‘azole’ resistant Candida species among late presenting AIDS patients in northwest Ethiopia